The results of the application tumor markers in complex diagnostics investigations at a stage of surgical treatment of colorectal metastases of the liver


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Abstract

The results of the application tumor markers (CEA, CA199, CA242) in complex tool researches at a stage of surgical treatment of colorectal livers’ metastases are considered in this article. The program consists of 60 patients diagnosed with colorectal cancer. Oncomarkers levels were defined by immunohemoluminescentic method before radiofrequency ablation of livers’ metastases and in 1, 3, 6 and 12 months after operation. Before surgical treatment individual oncomarkers levels were higher then discriminant concentration and depended of the sizes, volume and degree of a differentiation of a metastatic tumor. The researches have proved the efficiency of this oncomarkers in early diagnostics of relapses and a progression process at a stage dispensary observation after surgical treatment of livers metastases.

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Результаты применения онкомаркеров в комплексе диагностических исследований на этапе хирургического лечения колоректальных метастазов печени
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About the authors

O I Kaganov

References

  1. Давыдов, М.И. Смертность населения России и стран СНГ от злокачественных новообразований в 2006г [Текст] / Давыдов, М.И., Аксель Е.М. // Вестник РОНЦ им. Н. Н. Блохина РАМН. – 2008. – №2. – 92c.
  2. Levy, M. Tumor markers in staging and prognosis of colorectal carcinoma [Texts] / Levy M., Visokai V., Lipska L. // Neoplasma. – 2008. – Vol.55, № 2. – P. 138 – 142.
  3. Косырев, В. Ю. Лучевые методы диагностики в оценке изменений в зоне радиочастотной термоаблации опухолей печени [Текст] / Косырев В. Ю., Долгушин Б.И., Рампрабанантх С. С соавт. // Вестник РОНЦ им. Н. Н. Блохина РАМН. – 2008. – Т. 19, №2. – С. 35 41.
  4. Долгов, В.В. Иммуноферментный анализ в клиникодиагностических лабораториях [Текст] / Долгов В.В., Ракова Н.Г., Колупаев В.Е., с соавт. // Москва: «Триада», 2007. – С. 183.
  5. Bilchic, A. Prognostic Variables for Resection of Colorectal Cancer Hepatic Metastases: An Evolving Paradigm [Texts] / Bilchic A., Poston G., Adam R.// J.Clin. Oncol. – 2008. - Vol. 26, N 33. - P. 5320-5321.
  6. Sikorska, H. M. Carcinoembrionic Antigen [Texts] / Sikorska H. M., Fuks A., Gold P. // Sell St. (ed.). Serological Cancer Marcers.– N. Jersey: Humana Press. – 1992. – P.47 - 97.
  7. Levy, M. Tumor markers in staging and prognosis of colorectal carcinoma [Texts] / Levy M., Visokai V., Lipska L. // Neoplasma. – 2008. – Vol.55, № 2. – P. 138 – 142.
  8. Kuusela, P.CA 242 [Texts] / Kuusela P., Haglund C., Jalanko H.// Sell St. (ed.). Serological Cancer Marcers.– N. Jersey: Humana Press. – 1992. – P.429 - 435.

Copyright (c) 2011 Kaganov O.I.

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